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Weeks 5-8: Early Body Composition Changes What to Expect: Week 6-8: First noticeable weight changes for most users Improved insulin sensitivity (measurable via bloodwork) Better recovery from workouts Gradual fat loss (1-3 pounds total) Clinical Timeline: Research indicates most significant metabolic changes occur during this period

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Our small cross-sectional analysis of parallel blood and muscle samples from a set of healthy subjects showed that muscle NAD + decreases during aging, while blood levels were stable