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For instance, both semaglutide and some antidepressants (particularly SSRIs or SNRIs) can cause gastrointestinal issues such as nausea or diarrhea, which may intensify when taken together. GLP-1s and depression Experts continue to explore the potential effect that taking a medication like semaglutide could have on your mental health

Gastrointestinal adjustment in the first weeks mild nausea, slower digestion, occasional reflux is also widely reported and typically settles with titration

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One kit can typically last up to 12 weeks for new users following a gradual dosing schedule