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Wanner C, Frstner-Wanner S, Rssle C, et al

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Since the launch of Wegovy, Zepbound (tirzepatide) received FDA approval for the treatment of chronic weight management at the end of 2023, offering even more weight loss in clinical trials (20.9%) and a slightly different mechanism of action

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2 Changes in pH or ionic strength : For example, His-tagged proteins are eluted with low pH buffers or high concentrations of imidazole

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