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Cellular senescence was assessed by SA--galactosidase staining (SA--gal staining) using senescence -galactosidase Staining Kit (Cell Signaling Technology, Beverly, MA, United States) according to the manufacturers instructions

A subsequent combination of the modelling of the pre-trained and the post-trained deep learning algorithm leads to an overall accuracy of 86%

Comprehensive evaluation of PK, stability, and clinical considerations helps R&D teams choose the optimal cleavable linker, ensuring maximal therapeutic effect while minimizing adverse reactions: Cleavable linkers play a critical role in bioconjugation, enabling stable attachment of target molecules to active payloads while ensuring precise release under specific conditions

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