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Unlike sterile water or saline, bacteriostatic water allows repeated withdrawals within 28 days, but should never be injected alone

This action results in multiple effects on the liver, including induction of CYP1A1, CYP1A2 and CYP1B1

However, experts in the area generally concur that a combination of data from multiple endpoints is needed to discriminate sensitizing and/or irritant substances in vitro

Given that GS effectors have no appreciable rate of ATP turnover when supplied with canonical substrates, yet all display perfect conservation at the catalytic arginine, we infer that GS-like effectors possess a distinct catalytic activity, which may involve alternative substrate(s)