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Serotonin is critical for mood processing and emotional regulation in brain areas such as the amygdala and hippocampus (Hervas et al., 2000

Studies have also found that depleted amounts of butyrate-producing bacteria in ASD individuals, such as Faecalibacterium and Coprococcus , can counteract the leakiness of the gut (Figure 4) [192,193,194]

In brief, atorvastatin can significantly regulate the serum LDL-C level in model animals by regulating the PPAR signaling pathway and HMGCR gene expression