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Bottom line Mounjaro (tirzepatide) is a GLP-1 and GIP dual receptor agonist containing the same active ingredient as Zepbound, a weight loss drug made by the same manufacturer, Novo Nordisk

In the CY 2025 OPPS/ASC proposed rule (89 FR 59213 through 59222), we stated that we continue to believe diagnostic radiopharmaceuticals are always intended to be used with a diagnostic nuclear medicine procedure and function as supplies when used in a diagnostic test or procedure, generally making it appropriate to package payment for them with payment for the related nuclear medicine procedure

If the UR was 2.0, and the inhibition rate was 50% after treatment with a known transporter inhibitor, the compound was considered a substrate for the SLC transporter

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