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Rapid fat loss releases stored estrogen, which can cause menstrual irregularities, mood changes, and other hormonal symptoms

(2016) published in Diabetes Care evaluated the addition of a DPP-4 inhibitor to existing GLP-1 receptor agonist therapy and found no significant additional reduction in HbA1c compared to GLP-1 agonist monotherapy

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For the incretin crowd that has the MOA of tirzepatide all figured out here is some new intriguing mouse and primate data from @Amgen with a GIPR antagonist-GLP1R agonist antibody #weightloss #obesity #T2D @CellRepMed cell.com/cell-reports-m For the incretin crowd that has the MOA of tirzepatide all figured out here is some new intriguing mouse and primate data from @Amgen with a GIPR antagonist-GLP1R agonist antibody #weightloss #obesity #T2D @CellRepMed cell.com/cell-reports-m Join the conversation