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When men receive TRT, the body often suppresses its natural testosterone and sperm production, leading to potential issues like testicular shrinkage and infertility

In addition, elevated mannose, a key monosaccharide involved in glycoprotein synthesis, could point to disrupted glycosylation processes or broader shifts in carbohydrate metabolism 24

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While it is not a direct cure for side effects, glutathione supports liver health and cellular energy, which may help reduce the fatigue and general malaise some people feel when starting semaglutide