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Eligible publications investigated the potential associations between phytonutrientsincluding polyphenols, carotenoids, glucosinolates, and organo-sulphur compoundsand FM through mechanisms such as oxidative stress, inflammation, modulation of the gut microbiota, or SIRT1 regulation, in human studies or animal models

For MC4R antagonism studies in neuronal culture, the 1100 nM range is common

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