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It was easy to find that the results from the discovery cohort showed evidence of a significant association (OR = 0.24, 95%CI: 0.080.74, P = 0.013), whereas the results from the validation cohort, although suggestive of an association between GLP-1R expression and a low risk of developing DR, were not statistically relevant (OR = 0.61, 95%CI: 0.321.21, P = 0.161), a result that could be attributed to underlying differences in individual samples

Taken together, endometriosis organoids have facilitated deeper understanding of hormonal dysregulation and inflammatory pathways driving ectopic endometrial tissue implantation and proliferation

c normally resides within the cristae of the IMM and is sequestered by narrow cristae junctions