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& Macheroux, P

It should be noted that these studies measured total Cbl levels, but as previously mentioned, the biologically available form of Cbl, TCN2-Cbl, comprises only approximately 2030% of the total Cbl level, which may lead to a significant number of false negatives for clb deficiency

MET expression can be detected at a sub-cellular level in the growth-cone of P0 mice developing cortical tissue as well as in cultured hippocampal neurons, suggesting a functional role mediated by MET in neuronal growth (Peng et al., 2016)

Injecting into abdominal subcutaneous tissue places the peptide near target organs while providing systemic distribution