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Aerobic training can improve fatty acid oxidation, enhance muscle metabolism, regulate insulin sensitivity, and improve amino acid and iron homeostasis, thereby mitigating the adverse effects of ferroptosis

A systematic review and meta-analysis finds that GLP-1-based treatments drive clinically meaningful weight loss mainly through fat reduction, but experts warn that preserving muscle remains essential for long-term metabolic health

And with the right combination of nutrition, exercise, and supportive therapies, patients can preserve lean mass while still benefiting from the powerful fat-reducing effects of these medications