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Delayed gastric emptying : By slowing the rate at which food leaves the stomach, GLP-1 agonists help moderate post-prandial glucose excursions and promote satiety

[33] broadened the scope to 26 studies ( n = 3,020), including both metabolic RCTs with secondary psychiatric outcomes and a small number of trials in clinical populations (e.g., substance use disorders)

First, beta arrestins and Gaq can both internalize the GLP- 1 receptor, and multiple ligands can affect internalization

Common side effects with tirzepatide are usually gastrointestinal in nature including nausea, vomiting, diarrhea, or constipation but they tend to be mild to moderate and diminish as the body adjusts to initial dosing