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arginine has a predominant positive net charge below pH 12.0, thus for anion exchange the pH elution gradient with a solvent comprising an organic modifier could begin below pH 12.0 to elute the target GLP-1 moiety and end the gradient above pH 12.0 thereby subsequently removing an undesired form comprising an extra arginine residue

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But as a significant body of research now shows, excessive sugar consumption can be devastating for our health