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GLP-2R is expressed in the gastric mucosa in a subpopulation of fundas gland cells (Li et al., 2017) (Table 3)
A novel GLP-1/GIP dual receptor agonist protects from 6-OHDA lesion in a rat model of Parkinsons disease
Potential advantages Often a strong option for patients with significant reflux May be especially helpful for patients with type 2 diabetes or metabolic disease Can be used as a revision option after Lap-Band or sleeve in selected patients May provide more weight loss for some higher-risk or higher-BMI patients Long track record in bariatric and metabolic surgery Important considerations More complex anatomy than gastric sleeve Higher need for lifelong vitamin and mineral compliance Dumping syndrome can occur, especially with high-sugar foods NSAID and steroid use may be restricted because of ulcer risk Requires careful long-term follow-up Which Procedure Might Be the Best Fit
In a mouse model of influenza, the GLP-1 receptor agonist liraglutide not only inhibited the inflammatory response and improved survival rates but also significantly alleviated induced lung inflammation [94]
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