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From CircumSTANCE: October 6, 2021 Multisystem inflammatory syndrome in children (MIS-C) is a serious condition that appears to be linked to coronavirus disease 2019 (COVID-19)

Besides polysaccharide-based nanoparticles, nanoparticles made of other materials can also activate DCs, such as RNA-lipid complex (RNA-LPX) can precisely and effectively target DCs in vivo , where LPX protects RNA from extracellular ribonucleases and can mediate the efficient uptake and expression of DCs to encoded antigens, triggering plasmacytoid DCs and activating DCs in situ maturation (106)