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Tirzepatide carries a boxed warning regarding thyroid C-cell tumors observed in rodent studies, though there is no established link to human thyroid cancer

Researchers want to understand whether semaglutides action on GLP-1 receptors could change how the thyroid produces hormones

Notably, limited data were available for people with BMI 40 kg m 2 , the elderly, adolescents and people with overweight (BMI 25 kg m 2 and 25 kg m 2 ), with a treatment duration of at least 48 weeks, which compared OMMs with the specific indication of obesity treatment with either placebo or other OMM