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(1984a) c 182 30(76) NA 21(79) 21(67) NA NR 5(79) NA 92 38(79) NA 9(79) 20(66) NA NR 2(77) NA 0 24(77) NA 3(78) 48(73) NA NR 0(76) NA ------------------------------------------------------------------------------ a Only animals that survived for 24 months were included, because these tumours appeared after the 18-month interim sacrifice

Fifteen-point mutation types have been identified in human MTHFR, the most common and important of which is the mutation in C677T , which manifests itself in three genotypes, CC, CT, and TT