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While APEX2 and HRP both showed BP labeling on the cell surface and in the ER lumen, LaccID was exclusively active on the cell surface, with no labeling detected from ER-targeted LaccID (Fig

GLP-1 (Glucagon-Like Peptide-1) agonists mimic a naturally occurring hormone in your body that regulates appetite and blood sugar

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(3) Multitargeted therapy: BBR-isoliquiritigenin (ISL) dual therapy attenuates adipose inflammation and dyslipidemia via IRS1-PI3K-Akt pathway activation in DIO mouse, while BBR-catechin-capsaicin polypharmacology outperforms monotherapies in 3T3-L1 adipocytes [181, 195]