Med Oncol 38:138 Alfhili MA, Alamri HS, Alsughayyir J, Basudan AM (2022) Induction of hemolysis and eryptosis by occupational pollutant nickel chloride is mediated through calcium influx and p38 MAP kinase signaling
White Metallomics Research by Clare Duncan et al., published in Metallomics
They are generally not recommended for patients with a personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia syndrome type 2 (MEN2), those who are pregnant or breastfeeding or planning pregnancy, patients with a known allergy to the medication, severe gastroparesis or serious digestive motility disorders, active pancreatitis or significant pancreatitis history, serious gallbladder disease, certain kidney conditions, or active eating disorder concerns
However, this physiological action directly overlaps with the pathological mechanism of gastroparesis, which is characterized by abnormally slowed gastric emptying