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Loss of appetite While this supports weight loss, excessive loss of appetite may require dietary adjustments

CHBS is as an oversample of the national KFF Employer Health Benefits Survey, allowing comparisons between the coverage available to workers in California and the nation overall

A Cochrane systematic review of randomized trials for melasma found combination therapy more effective than single agents (a Cochrane systematic review of randomized trials for melasma), and a study in Middle Eastern skin confirmed a tretinoin and hydroquinone combination was effective and tolerated in deeper skin tones (a study of a hydroquinone and tretinoin combination for melasma in deeper skin tones)

[DOI] [PMC free article] [PubMed] [Google Scholar] 178.Mccarty M.F., Lerner A