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The critical role of the SLC46A1 encoded transporter in intestinal folate absorption is evident in individuals with an inherited form of folate malnutrition (hereditary folate malabsorption, HFM) that results from mutations in the SLC46A1 gene

doi: 10.1016/S0002-9440(10)65601-5 45 PakalaRWatanabeTBenedictCR

Because it is in an oral dissolving film formulation, it is absorbed through the oral mucosa, so it is absorbed more quickly and effectively than it is absorbed into the stomach and intestines and is recognized enough to be introduced in SCI-level research papers

If either or both of these values are over the recommended range then it would be a good idea to supplement with both folate as well as vitamin B12