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Bioavailability and why it matters for frequency Injectable semaglutide achieves approximately 89% bioavailability

For people in this BMI range, GLP-1 therapy sometimes serves as a bridge to other interventions or as an alternative to bariatric surgery

Gastrointestinal Effects GLP-1 medications have significant effects on the digestive system: They slow stomach emptying, increasing feelings of fullness They reduce gastric acid production They may help with inflammatory bowel diseases They enhance gut barrier protection They have anti-inflammatory effects in the digestive tract While these effects help with weight loss and blood sugar control, they can also cause side effects like nausea, vomiting, and diarrhea