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N-acetylcysteine is a chemical reducer of disulfide bonds via its free sulfhydryl groups may interact with the extracellular disulfide bridges of angiotensin II receptor, alter its tertiary structure, and inhibit the binding of angiotensin II to its surface receptors (AT 1a receptors) with subsequent attenuation of signal transduction and cell action

NAC, the acetyl derivative of L-cysteine, is more stable than L-cysteine, and can convert into L-cysteine after being absorbed

doi: 10.1080/19490976.2021.1880221 30