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Retatrutide is an investigational medicine that isnt licensed by the MHRA in the UK as of May 2026

Powerful glycemic control with compelling weight loss with Ozempic (semaglutide) injection 1 (semaglutide) injection 1 Ozempic is not indicated for weight loss Ozempic vs Lantus and Ozempic 1 mg vs 2 mg 1 Primary endpoint: change in A1C from baseline SUSTAIN 4: vs study-titrated Lantus 1,5 In insulin-nave adult patients with type 2 diabetes on metformin sulfonylurea Mean change in A1C from baseline at Week 30 Mean baseline A1C: 26% of insulin patients titrated to goal by Week 30

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Based on the initial data obtained 10-15 years ago regarding the neuroprotective effects of GLP-1RA in rodent models of stroke and neurological diseases, it has been suggested that these non-pancreatic effects may be beneficial for patients with T2DM and neurological comorbidities [5]