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On the other hand, viral protein sequences could form complexes with porphyrin, affect heme on the 1- chain of Hb, and release free iron 147
When GSH is depleted or GPX4 is inactivated, lipid peroxides accumulate, triggering ferroptosis (Liang et al., 2022)
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TMAO induces ERS via PERK/FoxO1 activation, decreasing insulin receptor expression and causing insulin resistance (81)
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