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The most common error pattern: researchers assume vial labels represent exact peptide mass when lyophilised powders routinely contain 512% overfill to compensate for handling loss

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What has been lacking is an integrated and quantitative understanding of the kinetics of APAP metabolism, of how APAP dosage affects NAPQI synthesis and GSH concentrations in the liver, of how NAC stimulates the synthesis of GSH, and of how the dosage and timing of NAC affect detoxification of NAPQI