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Other agents like dulaglutide (Trulicity) and liraglutide at lower doses (Victoza) are approved only for diabetes treatment
Anadem Publishing, 559 - 565, 2019
Taken together, our observations indicate that HNF4, SAA metabolism genes, and SAA metabolism are positively linked in human liver tumors and cell lines, and that SAA metabolism is altered in HNF4-negative mesenchymal liver cancer cell lines
The selectivity of the peptide is further discussed by the researchers, who suggest that senescent cells may depend more strongly on FOXO4-mediated control of p53 localization and activity, so disrupting that node might preferentially remove cells that are already operating close to an apoptotic threshold
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