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We identified a previously unknown metabolites profile in pericardial fluid of IHD patients compared to non-IHD subjects, which is to some extent different from that observed in the blood, highlighting that the pericardial fluid has its own unique environment

This enzyme catalyzes the N-methylation of nicotinamide using S-adenosyl-L-methionine (SAM) as a methyl donor, effectively creating a "metabolic drain" that depletes both NAD+ precursors and cellular methylation capacity

TRIF: TIR domain containing adaptor molecule 1

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