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Choosing between GLP-1 and GLP-2 (GLP-3 is not a current option) depends entirely on your health goals and conditions: Choose GLP-1 If Youre Focused On: Blood sugar control and diabetes management Weight loss and appetite suppression Metabolic health optimization Cardiovascular risk reduction Overall metabolic syndrome improvement Choose GLP-2 If Youre Dealing With: Short bowel syndrome Inflammatory bowel disease Malabsorption issues Intestinal damage or injury Chronic gut inflammation Need for improved nutrient absorption Consider Medical Consultation Neither GLP-1 nor GLP-2 should be started without proper medical evaluation

J Pharmacol Exp Ther 2013;344:141-54