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Carcinogenesis 30(6):997-1002, 2009

1 H NMR data are presented with the following: Chemical shifts () are reported in ppm relative to residual solvent peaks as internal standards, multiplicity (s = singlet, d = doublet, t = triplet, q = quartet, m = multiplet and br = broad), coupling constants ( J ) in Hz and integration

Understanding the potential for these symptoms helps patients and healthcare professionals anticipate and manage them effectively during the course of treatment

Visual Format: Side-effect and safety matrix Key Labels: Topical irritation, allergic reaction, formulation sensitivity, wound-care context, injectable route, limited safety data, peptide impurities, immunogenicity risk Suggested Layout: Create a three-column matrix: Topical products, Wound-care study context, and Injectable or compounded preparations. Under each column, list route-specific safety considerations using short, neutral labels