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At the outset of the project, in 2020, a targeted literature review was performed, for each endpoint, utilising expert knowledge in the fields of nuclear receptor activation, adipogenesis, nutrition and metabolic disruption, together with (guidance from) highly relevant well-documented reviews, to focus and retrieve pertinent chemical and target endpoint literature evidence

According to the American Lung Association, smoking marijuana damages the lungs first line of defense against infection by killing cells that help remove dust and germs

Several studies have explored a combination approach to enhance the skin permeability of therapeutic macromolecules to address this limitation