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Based on preclinical studies, a systematic review of the neuroprotective mechanisms of GLP-1RA-based therapy in ischemic stroke [67] has shown that administration of drugs of this family before, during, or after an experimental stroke in animals with and without diabetes modulates an acute inflammatory response secondary to brain ischemia, reducing inflammation, endothelial dysfunction and excitotoxicity, as well as decreasing oxidative stress and apoptosis
By integrating these strategies, clinicians can support patients in achieving the metabolic benefits of GLP-1 therapy whilst safeguarding long-term skeletal health
We also expect increasing consumerization which essentially means people paying out of pocket for lower-priced versions of these drugs, particularly in markets outside the US as they grow
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