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MPNST histologic features include monomorphic spindle cells with broad, intersecting, herringbone fascicles, alternating hyper- and hypocellular areas, a high mitotic count, and geographic necrosis [2]

also showed the same trend in knee symptoms and daily activity progression using the mean KOOS score in ten participants with degenerative meniscus tears without osteoarthritis according to Stoller classification after 3 months and 6 months of follow up (i.e., KOOS: 56.6 15.7 baseline, 70.2 16.8 post- 3 months, 72.7 18.5 post- 6 months, p = 0.0007)

Finally, some safety issues for long-term treatment of FGF21 analogues, such as cardiovascular side effects and bone loss, remain unresolved