Day 1 Right abdomen (systemic) Day 2 Left abdomen (systemic) Day 3 Right upper back flank (local) Day 4 Left upper back flank (local) Day 5 Right abdomen (systemic) Day 6 Left abdomen (systemic) Day 7 Alternate back flank (local) For thoracic spine injuries specifically, local injection near the affected area may provide additional benefit by delivering higher local concentrations while still achieving systemic distribution
Meyerhoff O, Mller K, Roelfsema MRG, Latz A, Lacombe B, Hedrich R, Dietrich P, Becker D (2005) AtGLR3.4 , a glutamate receptor channel-like gene, is sensitive to touch and cold
Tesofensine is generally considered more potent for direct appetite suppression studies due to its neurological mechanism of action
Vajda FJ, OBrien TJ, Hitchcock A, Graham J, Cook M, Lander C, et al