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Therefore, AX reactivity and conjugation to carrier molecules have been the subject of thorough investigation ( Initial assays preincubating proteins with reducing agents before treatment with AX showed a clear decrease in AX-protein adduct formation in the presence of DTT, whereas the effect of GSH was less consistent ( Figure 1 )

Still, they can cause side effects such as nausea, diarrhea, constipation, or vomiting, especially at higher doses

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Autophagy 12(4):7056 Wilson AG (2008) Epigenetic regulation of gene expression in the inflammatory response and relevance to common diseases