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Although the use of traditional medications, DMARDs, and innovative biologic agents has collectively improved treatment outcomes, numerous patients exhibit insufficient responses to existing therapies or adverse side effects, highlighting the necessity for novel treatment strategies (176)

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A 15-year follow-up study published in the Bulletin of Experimental Biology and Medicine (Khavinson et al., 2011) examined the geroprotective properties of pineal-derived peptides, with findings supporting long-term benefits on aging trajectory