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GLP-1RAs affects the central nervous system, including reducing appetite, improving diet control, increasing satiety, reducing calorie intake, etc

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It tends to be associated with other malformations of the genitourinary tract

Unlike classical T1D with almost only hyperglycemia, T2D is just one component of MDS, and is often accompanied by other components of MDS, such as overweight/obesity (preobesity might be a more appropriate term instead of overweight since obesity is not determined only by weight), metabolic dysfunction associated steatotic liver disease (MASLD), dyslipidemia