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detected GLP-1R protein expression by immunohistochemistry in mouse coronary endothelial and smooth muscle cells [35]

Moreover, oxidative stress makes the kidney tissue susceptible to damage by various alterations including the promotion of lipid peroxidation, protein modification, and DNA damage, leading to cell death [14]

Meanwhile, myeloid-cell specific GPX4 haploinsufficient mice presented with SLE-like manifestations such as spontaneous skin lesions and systemic damage, further validating that ferroptosis of neutrophils serves a critical role in the pathogenies of SLE

When nausea, vomiting, or diarrhea occur as side effects of GLP-1 medications, dehydration can leave you feeling even more fatigued