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Conclusion: Our nonclinical studies demonstrate how a single, brief exposure to NTLA-2002 durably edits the KLKB1 gene in hepatocytes, resulting in deep, persistent reductions in prekallikrein, even through partial liver resection, suggesting a permanent effect

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Garcia-Prez ME, Stevanovic T, Poubelle PE

For the complete quality framework, see How to Verify Peptide Quality: COAs, Third-Party Testing & What to Look For