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Key takeaways: GLP-1 medications are primarily used for weight loss, but are increasingly being explored in relation to PCOS and perimenopause Early evidence (mainly in women with obesity and PCOS) suggests GLP-1s may improve insulin resistance and support more regular menstrual cycles and ovulation There is currently limited research on how GLP-1 medications affect periods, fertility, PMS, or menopause symptoms in the wider population Period tracking apps like Clue may help users monitor cycle and symptom changes while using GLP-1 medications 1