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3, significant superiority in primary CV outcome was observed in three CVOTs using GLP-1 RAs (liraglutide OD in LEADER [56], dulaglutide OW in REWIND [36], and semaglutide OW in SUSTAIN 6 [non-inferiority and superiority were demonstrated in SUSTAIN 6 and pre-specified sensitivity analyses, respectively] [37])

This analysis provides a useful overview of 18 studies, and also demonstrates that male sex and younger age may be associated with a stronger protective effect of UA

Some people find they tolerate alcohol differently after starting a GLP-1 medication