Thus, we investigated mutants that result in defective respiratory chain complexes ( nde1 , nde2 , rip1 and cox17 ), chemical treatments to inhibit complexes of the respiratory chain (antimycin A (AntA), potassium cyanide (KCN) to inhibit complexes III and IV, respectively, and paraquat to induce mitochondrial oxidative stress), mutants of pathways counteracting ROS ( ccp1 , sod1 , sod2 ), and strains that express Mia40 and Erv1 under the control of regulatable promoters (Figure 5D and E
18 LiangQ.ShenN.LaiB.XuC.SunZ.WangZ.et al (2019)
A growing body of research points to inherited differences in the immune system as one reason for that variation
Recognizing these types underscores the importance of early diagnosis and intervention, as AFib tends to progress over time, potentially becoming more challenging to manage