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Similar content being viewed by others Introduction Schistosomiasis is a devastating but neglected tropical disease with more than 200 million people infected resulting in more than 200,000 deaths annually 1,2

Indeed, preventive injections with BGP-15 during chemotherapy-induced CC in healthy mice showed improved skeletal muscle mitochondrial viability and protection against ROS generation 260,261

Timeline matters: Expect 3-6 months for significant metabolic reset and body composition change

Glutathione peroxidase 4 (GPX4) reduces cytotoxic lipid ROS through converting GSH into oxidized glutathione (GSSG), resulting in the inhibition of ferroptosis [12]