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Due to their high translational value, NHPs help unravel complex immune and neurodegenerative mechanisms relevant to therapeutic modulation (Fulop et al., 2021)

In epithelium tissues, mechanical forces activate the RhoA signaling pathway, which triggers apical cell extrusion (a process functionally analogous to apoptosis in epithelial cells) [134]

This extended pharmacokinetic profile allows the investigation of sustained amylin receptor engagement over longer periods than would be possible with native amylin

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