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Alsunni, Nabil S

Ozempic (semaglutide) Disease area(s): Metabolic diseases Manufacturer(s): Novo Nordisk 2024 Sales (USD): $17.45 billion Why it sold so well: Novo Nordisks GLP-1 blockbuster for type 2 diabetes continued its impressive growth in 2024, with sales increasing by 26% year-over-year to DKK 120.3 billion ($17.45 billion)

However, using Gcgr / :Glp2r / mice, the authors demonstrate that GLP-1R signaling can still increase small intestinal length and weight compared to wild type, although not to the same extent as in Gcgr / mice (Koehler et al., 2015)