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doi: 10.1038/s41586-019-1707-0 41 ShimadaKHayanoMPaganoNCStockwellBR

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In stroke, metformin treatment has been shown to effectively protect the brain from ischemic injury either as a pre-stroke preconditioning agent or post-stroke drug treatment (Jiang et al., 2014

Additionally, lifestyle adjustments such as maintaining a consistent sleep schedule and avoiding known dietary triggers can significantly reduce the frequency of migraine attacks