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Pharmacokinetics (ADME) Absorption Well absorbed orally Rapid onset Distribution Highly protein bound (~99%) Metabolism Mainly hepatic metabolism Glucuronidation is significant Half-life About 23 hours But effect lasts longer due to enzyme inhibition Excretion Mainly via bile/feces Some renal excretion --- 5

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After a few weeks, Ive mostly noticed hydration and softness, but I think I need longer consistent use to really see brightening effects

Furthermore, GLP-1 receptor agonists have neuroprotective effects in the hippocampus, including enhanced neurogenesis and reduced apoptosis in studies primarily conducted in adult males (32,3841)