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Curr Opin Gastroenterol 28(2):166176

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This research offers further insight into this emerging safety signal, according to the study authors who noted in their Ophthalmology paper, Our novel, stratified analysis provides a more nuanced interpretation than previous pooled reviews, isolating a potential increased risk signal to observational data in the diabetes population only, a finding not corroborated by RCTs. These results are somewhat at odds with the narrative surrounding GLP-1 use and NAION risk that began in early 2024, but the researchers say they are confident in their methodology

Nutrition should evolve accordingly: prioritize protein (2535 g per meal), adequate hydration, and micronutrient-dense foods while your appetite is naturally reduced